|
DETAILS
|
| COMPOSITION |
Tablet: Each uncoated tablet contains: Paracetamol I.P. 500 mg.
Syrup: Each 5 ml contains: Paracetamol I.P. 125 mg. |
| INDICATIONS |
Pain and fever |
| MODE OF ACTION |
It acts on CNS to produce analgesia and anti-pyretic effect. It has negligible anti-inflammatory action in therapeutic doses. |
| ONSET OF ACTION |
30-60 minutes |
| DURATION OF ACTION |
6 hours. |
| ADVERSE EFFECT |
Nausea, epigastric distress. Rarely it can cause skin rash. Acute toxicity may result in hepatic failure. |
| CONTRAINDICATION |
Analgesic nephropathy. |
| SPECIAL PRECAUTIONS |
Long-term use may predispose to chronic renal disease. |
| DRUG INTERACTIONS |
Cholestyramine reduces absorption of Paracetamol. Activated Charcol if administered immediately afterwards reduces absorption of Paracetamol. Domperidone and Metoclopromide enhances absorption of paracetamol. Chronic excessive alcohol ingestion potentiates hepatotoxicity of Paracetamol. Effect of Zidovudine may be decreased. |
| DOSAGE AND ADMINISTRATION: |
Adults: 0.5-1 gm 3-6 times daily, maximum 4 gm / day may be consumed.
Children: 15 mg / kg / dose or 64mg / kg / day divided every 6 hours. |
| PACKING: |
Tablet: Strip of 10 tablets
Syrup: Bottle of 60 ml. |
Medicines for
Anti Diarrhoeal
Horn 
